Revd John Harries, vicar of St Mary the Virgin Church in the village, said the local community had been "ripped apart" by the disaster last Friday morning.
While three bodies have been recovered from the wreckage at the Wood Treatment Limited plant in Cheshire, one person is still unaccounted for.
Derek Moore, 62, has been identified as one of the victims.
Formal identification of the other two bodies is yet to take place but they are thought to be those of employees William Barks, 51, and Dorothy Bailey, 62.
Their colleague Jason Shingler, 38, is yet to be found.
The blast has been described as "worst incident of its kind" in a decade.
More than one hundred villagers attended the service, lighting candles to remember those who've died or been injured.
Revd Pam Butler, Methodist minister for Bosley, offered prayers for all those affected, "to settle their racing thoughts and help them to know they will not stand alone in grief".
After the closing hymn, Abide with Me, members of the congregation stood outside the church, some in tears, being hugged by well-wishers.
Revd Harries said: "The aim of today was to help people try and process everything that has happened over the last week. It is like there is a wound and this wound has been continually opened as the revelations come out of one body after the next.
"And people are raw with emotion, and I want us to be able to come together as a community and to support one another as we have been doing and lift each other up in prayer and just try and not relive, but think back to how our lives were last week, when in a matter of moments everything changed.
"It's ripped the community apart. This is really painful to get through, it's harrowing. But at the same time I can see our community coming closer together than it ever has done before and I have every confidence we will emerge stronger and even closer, if that is possible.
"But at the moment we are hurting tremendously.
"I was with the families yesterday as they went down to see the devastation down there and nothing can prepare you for that. It is very, very upsetting. Deeply upsetting."
