Bishop of Crediton Most Rev Sarah Mullally told Premier simple things like coffee mornings or encouraging telephone calls between those affected by isolation can make a significant difference.
She said: "Something for churches [to do] is to build on what they've been good at but actually become much more systematic about it, by putting people into contact, by using technology, as well as inviting people to coffee mornings or going out to have a coffee morning in somebody else's house."
Bishop Sarah spoke after new research by Age UK also concluded an additional half a million people go at least five or six days each week without seeing or speaking to anyone.
Speaking about the difference believers can make, she said: "If we can work together, I think we can very powerfully reduce the number of people who don't have interactions and, in doing that, help them not just emotionally and mentally but also physically."
Age UK released the statistics as it revealed the results of a trial which included well-connected people in the community, such as hairdressers and shopkeepers, being asked to help spot people struggling with loneliness.
Caroline Abrahams, Age UK's charity director, said: "This new analysis shows that about a million older people in our country are profoundly alone, many of whom are likely to be enduring the pain and suffering of loneliness."
The organisation says 88 per cent of those who joined the programme, which tested new approaches to combatting isolation, felt less lonely six to twelve weeks later.
Some participants were introduced to social groups or matched with volunteer befrienders, while others learned IT skills to help them stay connected with loved ones.
Caroline Abrahams went on to say: "Many also [said] they felt generally happier, more confident and more independent as a result.
"Unfortunately, there is no simple solution for loneliness, but our pilot programme shows we really can make a difference and provides crucial insights into how the problem can be successfully overcome."
In its latest report, 'No one should have no one: working to end loneliness amongst older people', Age UK warned of the toll loneliness takes on health services, especially because those affected are at a higher risk of heart problems, depression and dementia.
Louise Morse from the Pilgrims' Friend Society, a Christian charity which provides care for older people and offers resources to churches to aid engaging with older people, told Premier's News Hour: "It's really encouraging that they [churches] are aware about it and they are concerned about it [loneliness].
"Churches ...want to know how they can reach people in their own homes and how they can invite them in."
Click here to listen to Bishop of Crediton Sarah Mullally speaking with Premier's Alex Williams:
Click here to listen to Louise Morse from the Pilgrims' Friend Society speaking with Premier's Alex Williams: