The Labour leader says he'll be spending the Easter weekend with his family in Doncaster but will remember those who are targeted because of their religious beliefs.
He said: "According to the International Society for Human Rights, Christians are the victims of 80 per cent of all acts of religious discrimination in the world today.
"We must all do everything we can to speak out against this evil and work to alleviate the suffering of those who are persecuted simply for their creed."
Mr Miliband also praised the role churches and Christian charities play in supporting those in poverty: "But we don't need to travel far to find families facing fear and uncertainty.
"Over two million children are now living in poverty in the UK. I have admiration for those church members and Christian charities that provide support and hope to those in need.
Full text:
As Christians celebrate around the world, I would like to wish you all a happy Easter. As with many of you, I look forward to sharing this weekend with family in my constituency in Doncaster.
In the midst of the Easter celebrations our hearts goes out to those who face difficult times both overseas and closer to home. My thoughts are particularly with Christians in Syria, Iraq and other countries where the church suffers terrible persecution.
According to the International Society for Human Rights, Christians are the victims of 80 per cent of all acts of religious discrimination in the world today. We must all do everything we can to speak out against this evil and work to alleviate the suffering of those who are persecuted simply for their creed.
But we don't need to travel far to find families facing fear and uncertainty. Over two million children are now living in poverty in the UK. I have admiration for those church members and Christian charities that provide support and hope to those in need.
Over the Easter weekend millions of Christians will attend Easter events up and down the country. Through such gatherings, the church shares the story of the resurrection, and spreads the good news of Easter.
In the months to come I hope that we will all stand up for justice, serve the most vulnerable and work to positively transform our communities together.