Following his general audience the Holy Father invited the crowds to pray following the severe weather which has battered many parts of Britain.
He also asked for prayers for those affected by winter weather in the United States and South America.
He said: "I invite everyone to pray for the victims of the calamities which in these days have befallen the United States, Great Britain, and South America, particularly Paraguay.
"May the Lord give comfort to all these peoples, and may fraternal solidarity aid them in their need."
Meanwhile heavy rain and high winds brought on by Storm Frank are battering the UK, bringing fears of fresh flooding and further misery.
Thousands of homes in Scotland and Northern Ireland have been left without power as the third named storm in a month to hit the country caused widespread disruption overnight.
Gales and further heavy rain are expected in the already flood-ravaged north of England today, with people in some areas urged by officials to immediately evacuate their homes.
Three severe flood warnings are in place in Croston, Lancashire, with residents being urged to pack up and leave without delay, while across England and Wales more than 40 flood warnings and more than 80 lower level flood alerts are in force.
About 5,500 homes are without power in Scotland as gale-force winds and heavy rain batter the country, while more than 2,000 homes in Northern Ireland suffered overnight blackouts as Frank swept in from the Atlantic.
More than 60 flood warnings and 14 alerts have also been issued north of the border, while a red weather warning was issued overnight for the Isle of Man with up to 100mm (4 inches) of rain expected on high ground.
On Tuesday night, soldiers were sent in to evacuate homes around a storm-battered bridge after it started to collapse, prompting fears of flooding and a possible gas explosion.
A severe flood warning was issued for the bridge over the River Wharfe in Tadcaster, North Yorkshire, with the EA warning people to leave immediately because of a "significant risk to life".
The 18th-century bridge started to collapse into the swollen river at around 5pm, with a crowd gathering as masonry fell into the swirling torrent.