Clergymen have spoken out after it was announced the Void Gallery in Londonderry would feature American artist Andres Serrano's piece, called Immersion.
The photograph (full picture, below) shows Jesus on the cross inside a bottle of Mr Serrano's urine.
The artist's exhibition will also include pictures of detainees being tortured during the Irish Troubles.
It's thought to be the first time the set of pictures will be shown in Ireland.
Speaking on Premier's News Hour, Mark Bradfield from Bethel Baptist Church in Derry Londonderry said: "I don't think it's a very nice thing to do for the Man that gave us life, created everything that we have and gives us chance after chance, day by by to get right with Him.
"It's not exactly a wise or a nice thing to be doing. To me, it is one more brick in the wall of people drifting further and further away from the Lord. The Bible says, in Philipians 4:8, that we should think on good things."
Director of The Void gallery, Maoliosa Boyle, said: "Void's exhibition programme places a strong emphasis on social justice issues.
"With Serrano's Torture series, the viewer becomes' the onlooker' or 'the torturer' and they are faced with the inhumane and abject horror of torture.
"In a world where we have become numbed by the horrors of war through the media, Serrano confronts us with it in a brutal, uncomfortable way that we can't ignore."
Asked what message he has to The Void gallery, Mark added: "Well, there is a void in Derry. It is in people's hearts. They need to get saved and right with God.
"They could put something decent in [the gallery], something that will help people lift people up instead of destorying their view of God Almighty."
Andres Serrano, described his piece, Immersion, as "a reflection of my work, not only as an artist, but as a Christian."
Rev Roger Higginson, from Coleraine Free Presbyterian Church, told the Belfast Telegraph: "Men like these artists are actually quite cowardly because they make a mockery of Christ in a way that they wouldn't if it was Mohammed or the Muslim faith because that would put them in danger.
"His depiction of the Lord is offensive, not just to me as a man but it offends me greatly because this is how he portrays the Lord who gave up his life for all of us and this artist has thrown that sacrifice back.
"Perhaps if, as an artist you need to shock and cause offence and outrage to get your work noticed, it may be because of a lack of real talent."
The exhibition begins October 8th.
Click here to listen to pastor Mark Bradfield speaking with Premier's Aaron James:
