Aid has been unable to enter the city ravaged by fighting between Russian-backed government forces loyal to President Bashar al Assad and rebel forces.
It's thought two million people in the city have no access to clean, running water or food.
Yesterday at least four people were killed after what's believed to be a chlorine bomb fell on a rebel-held area of the city. Both sides have denied using chemical weapons.
Amid the humanitarian crisis, Russia proposed a daily three-hour ceasefire to allow aid to enter Aleppo, which was meant to start Wednesday morning, however there are reports that clashes are continuing.
The director of one of only a handful of aid charities allowed to work freely in Syria, who can't be named for his protection, has said that Syrians feel "left alone" in their suffering by the world and also called the international response from governments in ending the war "appalling", saying that the only way for it to end would be if every nation stopped supporting fighters on both the government and rebel sides.
Speaking on Premier's News Hour the director said: "It seems like whenever there is a military intervention, everyone is happy to chip in and pour in, obviously not the benefit for the civilians in opposition-held areas.
"Now when it comes to humanitarian aid, they [governments] are all united to leave the Syrians alone.
"We need to pray for peace. Syrians are a peaceful society - they want peace.
"We need to pray for the unity of Syria. Syria was always united, and we will still be united, if the foreign forces - everyone - leaves us alone."
Listen to Premier's Aaron James speaking to the director of the charity working on the ground in Syria: