The governing body of South American football, CONMEBOL, has had its last three presidents arrested and the majority of its other leading officials indicted on corruption charges by the US Department of Justice.
The latest president, Alejandro Dominguez, has signed an agreement with Pope Francis present, with his educational foundation, Scholas.
The Argentinean Pontiff has previously attended football matches throughout Latin America.
A statement from the governing body read: "CONMEBOL shares the Pope's vision of using sports to help educational models that benefit the development of skills and awareness.
"The aim of this joint action is to create social awareness about children in vulnerable situations."
The new executive committee has made a commitment to social responsibility one of its central themes.
CONMEBOL president Juan Angel Napout from Paraguay was arrested in December and two former presidents, Nicolas Leoz and Eugenio Figueredo, were indicted in May.
Others indicted include Brazilians, Ricardo Teixeira and Marco Polo del Nero, CONMEBOL secretary general Jose Luis Meiszner and Carlos Chavez CONMEBOL's former treasurer and the president of the Bolivian Football Federation.
The late Julio Grondona, the senior FIFA vice-president, was also named in the US indictment.