The Christian woman was sentenced to death under the country's blasphemy laws after being accused of criticising the Prophet Mohammed.
She's gone through several appeal cases and MPs are now calling for the highest judges in Pakistan to oversee the latest appeal.
The letter's been organised by Muslim MP Rehman Chishti and is being sent to Prime Minister Muhammad Nawaz Sharif and Chief Justice Nasir-Ul-Mulk
It says: "We feel strongly that a miscarriage of justice has taken place; that Asia Bibi has been falsely implicated and the evidence being used in her case has been fabricated.
"The International community is shocked and saddened at the unfairness of this decision and the treatment that she has received under Pakistan's justice system.
"We would urge that this case is heard by the Supreme Court on an urgent basis, taking into account that Asia Bibi has already spent four years in custody. The case should be heard by the full bench of the Supreme Court headed by the Chief Justice, taking into account the international concerns about this case, as it affects the credibility of Pakistan's judiciary.
"As friends of Pakistan, we feel this miscarriage of justice is tarnishing Pakistan's international reputation and we urge you to review this case as a matter of urgency."
The letter has been signed by the following MPs:
Rehman Chishti MP for Gillingham and Rainham
Dave Anderson MP for Blaydon
Tony Baldry MP for North Oxfordshire
Bob Blackman MP for Harrow East
Peter Bone MP for Wellingborough
Sir Peter Bottomley MP for Worthing West
Fiona Bruce MP for Congleton
David Burrowes MP for Enfield Southgate
Ronnie Campbell MP for Blyth Valley
Martin Caton MP for Gower
Oliver Colvile MP for Plymouth Sutton and Devonport
Michael Connarty MP for Linlithgow and East Falkirk
Alex Cunningham MP for Stockton North
Nic Dakin MP for Scunthorpe
David Davies MP for Monmouthshire
David Davis MP for Haltemprice and Howden
Mark Durkan MP for Foyle
Julie Elliot MP for Sunderland Central
Pat Glass MP for North West Durham
Roger Godsiff MP for Birmingham Sparkbrook and Small Heath
Damian Green MP for Ashford
Andrew Griffiths MP for Burton and Uttoxeter
Mike Hancock MP for Portsmouth South
Rebecca Harris MP for Castle Point
Sir Oliver Heald MP for North East Herfordshire
John Hemming MP for Birmingham Yardley
Gordon Henderson MP for Sittingbourne and Sheppey
Philip Hollobone MP for Kettering
Glenda Jackson MP for Hampstead and Kilburn
Stewart Jackson MP for Peterborough
Margot James MP for Stourbridge
John Leech MP for Manchester Withington
Jeremy Lefroy MP for Stafford
Julian Lewis MP for New Forest East
Ian Liddell-Grainger MP for Bridgwater and West Somerset
Naomi Long MP for Belfast East
Caroline Lucas MP for Brighton Pavilion
Mary Macleod MP for Brentford and Isleworth
Ann McKechin MP for Glasgow North
Stephen Metcalfe MP for South Basildon and East Thurrock
Madeleine Moon MP for Bridgend
Caroline Nokes MP for Romsey and Southampton North
Laurence Robertson MP for Tewkesbury
Adrian Sanders MP for Torbay
Jim Shannon MP for Strangford
Andrew Smith MP for Oxford East
Sir Nicholas Soames MP for Mid Sussex
Andrew Stephenson MP for Pendle
Sir Andrew Stunell MP for Hazel Grove
Valerie Vaz MP for Walsall South
David Ward MP for Bradford East
Angela Watkinson MP for Hornchurch and Upminster
Craig Whittaker MP for Calder Valley
Sammy Wilson MP for East Antrim