Responding to a public consultation, the organisation called for "bold steps" to be taken in tackling climate change, by supporting renewable and efficient energy instead.
A representative meeting of Quakers concluded: "We have faith we can tackle climate change and build a more sustainable future, but we know this is only possible if fossil fuels remain in the ground."
"Fracked gas is not the low-carbon solution some suggest and is incompatible with tackling the climate crisis. It is destructive of the environment, land and communities."
Bolton #Quakers support #Bolton Against #Fracking march up #rivingtonpike today @frackfreelancs - join us again Sat 6 May @PendleHillQuake pic.twitter.com/11EXAUA2x0
— Ian David McHugh (@IanDavidMcHugh) April 14, 2017
The Scottish government has implemented a moratorium - a temporary ban - on fracking and other unconventional oil and gas developments while the industry and its impacts are scrutinised.
A statement on its website said: "The Scottish Government has a big decision to make on the future of unconventional oil and gas in Scotland.
"The Scottish Government's position is to take a cautious, evidence led approach while we gather and consider evidence."
The 'Talking Fracking' consultation runs until 31st May 2017.
Quakers across Britain have already opposed moves to conduct fracking in other parts of the country, including proposed developments in Sussex and Yorkshire.
John Fitzgerald of South East Scotland Quaker Area Meeting said: "The economic claims in support of fracking are dubious - research shows it would only bring a small number of jobs over many decades."