Secretary of State Mike Pompeo was responding to a question from the Christian Broadcasting Network on whether the US President was like a modern day Esther from the Bible.
Speaking on the Purim holiday in which Jews celebrate the biblical rescue of the Jewish people by Queen Esther from the Persians, Pompeo said: "As a Christian, I certainly believe that's possible,.
"It was remarkable...the work that our administration's done to make sure that this democracy in the Middle East, that this Jewish state remains.
"I am confident that the Lord is at work here."
On Thursday, President Trump announced a change in US policy on the Golan Heights, a disputed territory that Israel has occupied from Syria since 1967.
Trump said it should be recognised as part of Israel - a move the Israeli Prime Minister said was a "Purim miracle".
Pompeo's not the first to claim God put Donald Trump in office.
Last year White House press secretary Sarah Sanders said that God "wanted Donald Trump to become president".
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